The film lacks explicit depictions of LGBTQ+ identities or non-cisnormative gender expressions. Character dynamics focus on biological survival and species conflict, leaving little room for queer subtext.

Primary agency and combat roles are concentrated among male protagonists. While female characters exist within the resistance, they often function in supportive or reactive capacities rather than driving the plot.

The production features a largely homogeneous Japanese cast. The narrative focuses on the biological distinction between Humans and Orphnochs rather than exploring ethnic or racial diversity.

The film deconstructs traditional social institutions by presenting a world where a corporation has supplanted the state. It engages with themes of systemic corruption and moral relativism.

There is no significant focus on neurodivergence or physical disabilities. Orphnoch transformations are treated as a species-wide evolutionary shift rather than a representation of individual disability.