The film explores fluid identities through biological mutation and mechanical merging. However, it lacks explicit depictions of same-sex intimacy or specific non-cisnormative gender identities.

Characters are defined by survival and violence rather than traditional social roles. While it disrupts gender hierarchies through chaos, it does not explicitly center on subverting masculinity or femininity.

As a Japanese production, the film presents a culturally specific, homogeneous environment. It does not focus on multiculturalism or interracial dynamics, reflecting its specific linguistic and cultural context.

The narrative rejects traditional moral purity through protagonists with dark secrets. It portrays a world where social order and institutions fail against systemic biological threats.

The Necro-borg transformations offer a radical, involuntary alteration of the body. These physical deviations grant characters monstrous agency, serving as sources of both terror and power.