The film lacks LGBTQ+ characters or non-heteronormative romantic arcs. The narrative focuses strictly on the biological threat and survivalist dynamics of the protagonists.

Susan Tyler serves as a highly capable female entomologist with significant professional agency. She drives the scientific investigation and avoids the typical damsel in distress trope.

A multi-ethnic cast, including Delroy Lindo, provides a diverse urban landscape. While not a non-white majority, the film avoids total homogeneity through significant characters of color.

The story critiques scientific and corporate hubris regarding human intervention in nature. It questions the perceived mastery and ethics of Western scientific institutions.

Representation is minimal. While biological mutation explores the 'uncanny valley,' these elements function as horror devices rather than depictions of characters with lived disability experiences.