The film lacks LGBTQ+ characters and does not explore non-heteronormative identities. The story focuses entirely on supernatural conflict and the core trio.

Liz Sherman provides a powerful presence with significant elemental agency. However, the narrative is driven by Hellboy, and female figures often serve as mythic archetypes.

The setting leans toward a homogeneous, Western-centric supernatural folklore. There is no evidence of intentional intersectional casting or non-human species used as metaphors for diversity.

The film follows a conventional monster-hunter structure without engaging in secularist or anti-Western critiques. It portrays the B.P.R.D. as a professional, structured authority.

Hellboy and Abe Sapien possess non-human physicalities, but these are treated as standard genre elements. They function as archetypal monsters rather than nuanced explorations of disability.