The story focuses on supernatural conflicts between Hellboy and elemental spirits. No LGBTQ+ characters or non-cisnormative identities appear in this action-adventure framework.

Liz Sherman provides significant elemental power and combat utility. However, the narrative remains centered on the male protagonist's journey rather than subverting traditional gender hierarchies.

The film uses non-human characters like Hellboy and Abe Sapien as metaphors for marginalized identities. The setting also incorporates Japanese folklore and mythological aesthetics.

The narrative follows traditional Western storytelling patterns and hero's journey tropes. It reinforces institutional authority through the B.P.R.D. rather than critiquing it.

Physical divergence is expressed through the characters' demonic and aquatic physiologies. These traits are framed as supernatural fantasy rather than specific explorations of disability.