The film lacks explicit LGBTQ+ characters or narratives. The story focuses exclusively on the romantic and intellectual partnership between Marie and Pierre Curie.

Marie Curie is portrayed as the primary driver of scientific innovation rather than a secondary figure. The film effectively subverts patriarchal hierarchies by highlighting her intellectual agency.

The narrative emphasizes Marie’s Polish heritage and her status as an immigrant outsider. However, the cast remains largely homogeneous within its European historical setting.

The film critiques Western institutions by showing how scientific discovery is repurposed for weaponry. It explores the tension between intellectual pursuit and the military-industrial complex.

Radiation exposure is depicted as a physical consequence of scientific work. There is a lack of neurodivergent or explicitly disabled characters with significant agency.