The film lacks LGBTQ+ characters or storylines. It operates within a traditional survival horror framework focused on biological contagion.

Female characters like Ángela Vidal hold central roles, and the ensemble shows a balanced gender distribution. However, the narrative adheres to conventional tropes without subverting gender hierarchies.

The cast is predominantly Spanish, reflecting the localized Madrid setting. The film offers minimal engagement with broader ethnic diversity or intersectional racial dynamics.

The story centers on the systemic failure of Western institutions like the military and medical protocols. This portrayal of institutional collapse serves the genre's tension.

There is no significant focus on neurodivergence or visible disabilities. Characters are defined by their physical capacity to survive the high-stakes environment.