The film explores a profound emotional connection between Penny Patterson and Koko that transcends species. However, it lacks explicit queer-coded character arcs or non-cisnormative identities.

Penny Patterson is positioned as a figure of significant authority and resilience. The narrative highlights her intellectual labor and agency while resisting traditional submissive tropes.

The documentary maintains a relatively homogeneous focus on its specific biographical subjects. There is no evidence of a diverse cast or intersectional racial blending within the central narrative.

The story challenges Western scientific institutions and zoo bureaucracies through Patterson's struggles. It explores subjective morality regarding animal rights and the sentience of non-human beings.

Koko’s use of sign language serves as a metaphor for non-verbal expression. This provides a narrative framework that mirrors the agency sought by those with communicative disabilities.