The film lacks any LGBTQ+ characters or non-cisnormative identities. The romantic arc remains strictly heteronormative, focusing entirely on the relationship between Sherman Klump and Denise Gaines.

Female characters like Denise Gaines possess professional agency as DNA specialists. However, their narrative purpose is largely tied to the male protagonist's emotional and romantic development.

The film centers a Black protagonist and a predominantly Black family unit. While providing visibility, it often uses these identities through a lens of slapstick and physical comedy.

The narrative reinforces traditional Western social structures and the nuclear family. It prioritizes conventional morality and the restoration of social order over any critique of Western institutions.

Themes of body image and physical difference serve as vehicles for alter-ego comedy. The portrayal lacks the nuance required to move beyond using transformation as a comedic device.