The film adheres to traditional heteronormative structures. There is no visible presence of non-cisnormative identities or narratives that critique these norms.

Female characters like Rebecca Chambers demonstrate significant intellectual agency and professional competence. Their presence in leadership and scientific roles prevents a purely patriarchal narrative.

The inclusion of international operatives like Liu Xue provides a more globalized security landscape. However, the cast stops short of a non-Western majority.

The story critiques corporate negligence through the Umbrella Corporation. Yet, it remains anchored in traditional Western paramilitary frameworks to restore order.

Disability is framed through biological mutation and the loss of bodily autonomy. These depictions serve as horror plot devices rather than nuanced portrayals of lived experience.